Women of childbearing age should discuss the risks and benefits of this medication, other treatment options, and use of reliable forms of birth control with their doctor. Taking this medication during pregnancy can cause birth defects, may lower your child's IQ, and may increase the risk of your child having certain brain/mental disorders (such as autism, attention deficit/hyperactivity disorder). Tell your doctor right away if you develop symptoms of liver problems or pancreatitis such as unusual tiredness, weakness, swelling of the face, stomach/abdominal pain, loss of appetite, dark urine, yellowing eyes/skin, or persistent nausea/vomiting. This may occur at any time during treatment and can quickly worsen. This medication has rarely caused severe (sometimes fatal) disease of the pancreas (pancreatitis). Children older than 2 years who might have these disorders should be closely monitored during treatment with divalproex sodium. Children younger than 2 years who might have these disorders should not use this medication. Talk with the doctor about the risks and benefits of using this medication in children younger than 2 years.ĭue to an increased risk for liver problems, people with certain inherited metabolic disorders (such as Alpers-Huttenlocher syndrome) should not use this medication. The risk of serious liver problems is increased in children younger than 2 years, especially if they have an inherited metabolic disorder, severe seizure disorder with mental retardation, organic brain disease, or if they take more than one seizure medication. Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first 6 months, to monitor this side effect. Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first 6 months of starting treatment.
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